We'll also explain mixing and matching vaccines from the different drug-makers. With cases, hospitalizations and deaths beginning to plateau, epidemiologists worry about another wave of COVID infections as cold weather drives people indoors and as the annual flu season begins to kick in, socking immune systems. The FDA-approved COVID vaccines have proven to be highly effective in preventing hospitalization, and those who are unvaccinated are 10 times more likely to be hospitalized.

With the new federal vaccine mandatesthe Biden administration aims to counter the surge and put pressure on anyone who hasn't been vaccinated. Antiviral drugs could also help. For more on COVID, here's the latest on COVID vaccines for kidswhat to do if you lost your vaccination cardthe difference between a booster and a third dose and breakthrough infections. The FDA authorized a Moderna vaccine booster for Moderna recipients age 65 years of age and older, and adults who are at high risk because of severe illness or exposure in their work setting. Those who are eligible can get their shots now.

Anyone eligible for a booster can get any of the available brands of coronavirus vaccines. What does the Moderna booster vaccine do? This includes looking at how new variants, like Delta, affect vaccine effectiveness.

Data Supporting Need for a Booster Shot Studies show after getting vaccinated against COVID, protection against the virus and the ability to prevent infection with the Delta variant may decrease over time. Although COVID vaccination for adults ages 65 years and older remains effective in preventing severe disease, recent data pdf icon[5 MB, 88 pages] suggest vaccination is less effective at preventing infection or milder illness with symptoms over time.

Emerging evidence also shows that among healthcare and other frontline workers, vaccine effectiveness against COVID infections is also decreasing over time.

This lower effectiveness is likely due to the combination of decreasing protection as time passes since getting vaccinated, as well as the greater infectiousness of the Delta variant. Data from small clinical trials show that a Pfizer-BioNTech or Moderna booster shot increased the immune response in trial participants who finished their initial series 6 months earlier. With an increased immune response, people should have improved protection against COVID, including the Delta variant.

The announcement came after both the Food and Drug Administration and the Centers for Disease Control and Prevention authorized booster doses for certain high risk groups last week.

Who is eligible for a booster shot? As of now, booster shots of the Pfizer vaccine are only available for individuals who were initially vaccinated with the Pfizer vaccine as well.

Those conditions include cancer, chronic lung diseases like COPD, asthma, cystic fibrosis and others; diabetes type 1 or 2 ; heart conditions like heart failure or coronary artery disease; being immunocompromised, or being overweight or obese. Those could include health care workers, teachers and child care providers, or food workers, according to the N.

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