Conclusion Psoriasis is associated with deranged iron status characterized by depleted iron stores with concomitant unmet cellular iron requirements. The magnitude of these abnormalities is particularly strong in patients with low body mass index.

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Whether iron deficiency may become a therapeutic target in psoriasis needs to be investigated. On the other hand, chronic inflammatory diseases are often associated with deranged iron status reflecting iron deficiency ID. Surprisingly, iron status has never been comprehensively investigated in these patients.

There are only few small observational studies, 12 — 15 which in fact have not investigated iron status itself, but rather anaemia in the context of potentially concomitant iron deficiency. Therefore, we aimed to investigate iron status among patients with psoriasis using both standard and novel biomarkers of iron status hepcidin and soluble transferrin receptor and relate these measures with the severity of the disease, the magnitude of pro-inflammatory activation, and the presence of extra-cutaneous complications including psoriatic arthritis and low body weightin comparison with healthy controls.

The lack of iron may be due to bleeding menstrual bleeding, ulcer, etc. For that reason, it is recommended que es en espaГ±ol mean corpuscular volume study ferritin and transferrin saturation to diagnose the iron-deficiency anemia. A mild microcytosis may be also due anemia of chronic disease, for example, in case of chronic inflammatory diseases such as rheumatoid arthritis or lupus.

Moderate microcytosis 65 - 75 fl in adults : A moderate microcytosis may be a sign of thalassemia. Thalassemia is a group of hereditary disorders in which the body produces an abnormal form of hemoglobin hemoglobinopathy.

¿Cuál es el valor normal del Volumen Corpuscular Medio (VCM)?

There are many types of thalassemia. A moderate microcytosis usually correspond to the least serious types like alpha thalassemia. Another possibility is due to a genetic condition called congenital sideroblastic anemia. Marked microcytosis 55 - 75 fl in adults : A marked microcytosis may be a sign of different types of thalassemiasuch as thalassemia intermedia, beta thalassemia minor or Hemoglobin H disease. Those are moderate types of thalassemia.

Which factors can reduce the MCV?

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Que es en espaГ±ol mean corpuscular volume Video

MCV blood test in hindi - MCV कम क्यों होता है, MCV नार्मल कैसे करें, MCV नार्मल के लिए क्या खाएं.

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